malaria symptom diagnosis
To prevent the emergence of resistance to the most recent antimalarial drugs which are therefore the most powerful, the WHO in collaboration with the pharmaceutical industry, is actively examining the advantages of associating several antimalarial drugs that have different mechanisms of action and rapidity of action, the difficulty of the clinical atypical form and biological pauci-parasitic form diagnosis, among patients who have followed a chemoprophylaxis treatment, means sometimes hospitalization and a multiplication of the diagnostic examinations.
The presumptive treatment still remains a necessity at times, in endemic zones, more especially in Africa, the treatment is given following a clinical diagnosis, where the major symptom is a fever.
If it is completely justified, this presumptive treatment of a febrile crisis does not provide a fully satisfactory solution, this attitude leads to the prescription of unjustified treatments for non-malarial fevers and increases the medicinal pressure exercised on the parasite.
Furthermore, the chemoresistance of Plasmodium falciparum imposes therapeutic choices with less well-tolerated and much more expensive molecules than chloroquine, resistance to these new molecules may also develop rapidly, if they are not used judiciously, only evidence of the parasite may provide a sure diagnosis and lead to appropriate treatment..
\'Malaria is the most important and the most widespread of the transmissible diseases, it threatens almost one third of Humanity, affects around 600 million people and is responsible, each year, for more than 2 million deaths.
parasite symptom
parasite treatment
Caused by microscopic parasites, Plasmodia, this disease is transmitted by the bite of certain mosquitoes, the Anopheles, its symptoms include bouts of a special type of fever, as well as an increase in the volume of the spleen and various other disorders.
But malaria may involve complications such as cerebral attacks causing a fatal coma, especially among young children living in malaria-endemic areas or among expatriates and tourists, globally, malaria thrives in various inter-tropical regions, with the obvious exception of the desert areas or high mountains.
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Beyond geographical or climatic factors, the frequency of the disease is essentially controlled by the mosquito vector, certain species are, in fact, more active than others.
This explains the frequency and the intensity of the infection in inter-tropical Africa and in certain regions of the Amazon Basin, on the other hand, the intensity of transmission is lower in other inter-tropical regions and especially in South East Asia, the agents of malaria, called Plasmodia, are microscopic parasites measuring a few thousandths of a millimeter, which always develop inside host cells.
Of the 4 plasmodial species that can live as a parasite in humans, Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and Plasmodium malariae, the most important is Plasmodium falciparum since it is both the most widespread and the only one capable of producing fatal complications, the Plasmodia develop inside red blood cells.
Impact Malaria: paludisme, information for the public and healthcare professionals - plasmodium falciparum, malaria africa.
